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21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17
InChi: InChI=1S/C25H37N3O4/c1-3-5-6-7-8-9-10-11-12-13-18-21(29)26-27-24(31)22-23(30)19-16-14-15-17-20(19)28(4-2)25(22)32/h14-17
ML241 (20 μM) shows no obvious inhibition of the appr 170 kinases tested
Chemical Name: ethyl 12-(2-{[(2R
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L-732138 ngo Red 21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17L 732138 is a selective, potent and competitive neurokinin 1 (NK 1) receptor antagonist with an IC50 of 2. 3 nM. L 732138 has 200 fold more potent in cloned human NK 1 receptors than cloned rat NK 1 receptors, and has > 1000 fold more potent than human NK 2 and NK 3 receptors. L 732138 can reduce hyperalgesia and has antitumor action. Product information CAS Number: 148451 96 1 Molecular Weight: 472. 38 Formula: C22H18F6N2O3 Chemical Name: [3,5